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FEBRUARY 20, 2025

Home-Based Ig Rx Reduces Infections and Antibiotic Use

By Heidi Splete
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Caroline Geremakis, MD

Adults with primary immunodeficiency diseases (PIDDs) who self-administered immunoglobulin replacement therapy (IgRT) at home had significantly lower infection rates and reduced use of antibiotics compared with those not employing home-based care with the medication, according to new data from a large managed care database.

Although IgRT is the standard of care for PIDDs, data on treatment patterns and healthcare resource use in patients who begin