A severe necrotizing form of mpox with a high mortality rate among people with HIV whose CD4 count was less than 200 cells/m3 was described at CROI 2023, in Seattle (presentation 173). The investigators think mpox should be classified as an AIDS-defining disease.
“The first key finding that we have is there was a very clear relationship between CD4 count, viral load and outcomes,” said Chloe Orkin, MBBCH, MSc, a professor of HIV medicine in the Center for