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OCTOBER 27, 2024

Twice-Yearly Lenacapavir Sets a New PrEP Standard


Originally published by our sister publication Pharmacy Practice News

By PPN News Staff

The results of an interim analysis from a second pivotal phase 3 clinical trial investigating the use of Gilead’s twice-yearly injectable HIV-1 capsid inhibitor, lenacapavir, found that it reduced HIV infections by 96% compared with background HIV incidence (bHIV).

The PURPOSE 2 trial (ClinicalTrials.gov Identifier: NCT04925752), a multicenter, randomized double-blind study, is evaluating the safety and