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APRIL 17, 2025

Ensitrelvir PEP Continues to Prevent SARS-CoV-2 Infection


Originally published by our sister publication Infectious Disease Special Edition

By Marie Rosenthal, MS

If given within 72 hours after clinical onset of COVID-19 in a household, oral ensitrelvir was effective in protecting household contacts from SARS-CoV-2 infection, according to a presentation at ESCMID Global 2025, in Vienna (abstract 03159).

Protection was consistently seen in all at-risk groups studied, including older household contacts, according to Frederick G. Hayden, MD, the Stuart S.