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DECEMBER 20, 2022

FDA Approves Adstiladrin, First Gene Therapy for Bladder Cancer

SPC News Staff

The FDA approved nadofaragene firadenovec-vncg (Adstiladrin, Ferring Pharmaceuticals), the first gene therapy for adults with high-risk bacillus Calmette-Guérin (BCG)-unresponsive non–muscle-invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumors.

Nadofaragene firadenovec-vncg is a nonreplicating adenoviral vector–based gene therapy containing the gene interferon alfa-2b, administered by catheter into the bladder once every