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MARCH 22, 2022

Nivolumab Plus Relatlimab Approved to Treat Metastatic Melanoma

Originally published by our sister publication, Clinical Oncology News.

By Dave Doolittle

The FDA approved a fixed-dose combination of the programmed death-1–blocking antibody nivolumab and relatlimab-rmbw, a lymphocyte activation gene-3–blocking antibody, to treat patients aged 12 years and older with unresectable or metastatic melanoma.

Patients treated with the combination, called Opdualag (Bristol Myers Squibb), showed a statistically significant improvement in progression-free