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SEPTEMBER 18, 2024

FDA Approves Keytruda With Chemo for Unresectable Advanced or Metastatic Malignant Pleural Mesothelioma


Originally published by our sister publication Clinical Oncology News

By Clinical Oncology News Staff

The FDA has approved pembrolizumab (Keytruda, Merck) with pemetrexed and platinum-based chemotherapy as first-line treatment of unresectable advanced or metastatic malignant pleural mesothelioma (MPM).

Efficacy was investigated in KEYNOTE-483 (ClinicalTrials.gov. Identifier: NCT02784171), a randomized, open-label trial in patients with unresectable advanced or metastatic MPM and no prior systemic