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OCTOBER 14, 2020

Dupixent Appears to Reduce Severe Asthma Exacerbations in Children

SPC News Staff

A pivotal phase 3 trial of dupilumab (Dupixent, Regeneron) met its primary and all key secondary end points in children aged 6 to 11 years with uncontrolled moderate to severe asthma, according to Sanofi, the parent company. 

In a broad type 2 inflammatory asthma patient population, defined as having elevated eosinophils (EOS) or elevated fractional exhaled nitric oxide (FeNO), dupilumab added to standard-of-care treatment significantly reduced asthma exacerbations and