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APRIL 18, 2022

Maintenance Rucaparib After Chemo Extends PFS in Some Metastatic Urothelial Cancers

Originally published by our sister publication, Clinical Oncology News.

By Wayne Kuznar

Maintenance therapy with the poly (ADP-ribose) polymerase (PARP) inhibitor rucaparib following platinum-based chemotherapy extended progression-free survival in patients with metastatic urothelial carcinoma that harbors a biomarker for DNA repair deficiency, the results of a trial showed.

The final analysis of ATLANTIS, a phase 2, randomized, double-blind, placebo-controlled trial, showed a median