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MAY 17, 2023

In UC, Tofacitinib and Ustekinumab Perform Similarly After Biologic Failure


Originally published by our sister publication Gastroenterology & Endoscopy News

By Ted Bosworth

CHICAGO—In biologic-experienced patients with ulcerative colitis, tofacitinib and ustekinumab achieve about the same rate of corticosteroid-free remission by 16 weeks, according to research presented at Digestive Disease Week 2023.

However, despite similar rates of corticosteroid-free remission (CFR), primary failure to a biologic and treatment with three or more biologics were associated