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SEPTEMBER 13, 2024

Twice-Yearly Lenacapavir for PrEP Reduced HIV Infections by 96%


Originally published by our sister publication Infectious Disease Special Edition

The results of an interim analysis from a second pivotal phase 3 clinical trial investigating the use of Gilead’s twice-yearly injectable HIV-1 capsid inhibitor, lenacapavir, found that it reduced HIV infections by 96% compared with background HIV incidence (bHIV). 

There were two incident cases among 2,180 participants, corresponding to 99.9% of participants not acquiring HIV infection in the lenacapavir