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OCTOBER 3, 2022

Double Checkpoint Inhibitors Plus TKI Improves Control of RCC

By Ted Bosworth

Originally published by our sister publication Clinical Oncology News

In patients with advanced renal cell carcinoma, the addition of the tyrosine kinase inhibitor cabozantinib (Cabometyx, Exelixis) improves progression-free survival (PFS) relative to a doublet checkpoint inhibitor (CPI) combination of nivolumab (Opdivo, Bristol Myers Squibb [BMS]) and ipilimumab (Yervoy, BMS). The data were presented as a late-breaker (abstract LBA 8) at the 2022 annual meeting of the European