By SPC News Staff
Researchers from the University of Plymouth, in England, showed that the antidepressant mirtazapine offered no improvement in agitation for people with dementia—and may be associated with increased mortality than no intervention at all (Lancet 2021;398[10310]:1487).
Agitation is a common symptom of dementia, characterized by inappropriate verbal, vocal or motor activity, and often involves physical and verbal aggression. The first intervention should be behavioral