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SEPTEMBER 30, 2016

FDA Grants Breakthrough Therapy Designation for AbbVie's Investigational HCV Regimen

By SPC News Staff

The FDA granted Breakthrough Therapy Designation for AbbVie's investigational, pan-genotypic regimen of glecaprevir (ABT-493)/pibrentasvir (ABT-530) (G/P) for the treatment of patients with chronic hepatitis C virus (HCV) who failed previous therapy with direct-acting antivirals (DAAs) in genotype 1 (GT1), including therapy with an NS5A inhibitor and/or protease inhibitor.

The designation is supported by positive results seen in AbbVie's Phase 2 MAGELLAN-1 clinical study.