Cell and Gene Therapies: A Review of Current and Future Treatments

In the last 15 years, cell and gene therapies (CGTs) have emerged as transformative treatments for diseases that previously had no approved therapy options. Gene therapy is defined as the repair, replacement, or deactivation of dysfunctional genes to reestablish normal function.¹ Cell therapy is defined as the transfer of autologous (from oneself) or allogeneic (donor) cellular material into