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GVHD

Optimizing Pharmacotherapy In Chronic GVHD

Chronic graft-versus-host disease can occur in a multitude of organs, often characterized by fibrosis or ...

JUNE 13, 2025

Long-Term Management of Solid-Organ and Hematopoietic Cell Transplant Recipients

The long-term success of solid-organ transplant recipients greatly hinges on effective maintenance ...

DECEMBER 18, 2024

Steroids Still the Mainstay Treatment for cGVHD

Corticosteroids remain an effective tool for treating chronic graft-versus-host disease, although they are ...

DECEMBER 15, 2024

FDA Approves Niktimvo for Chronic Graft-Versus-Host Disease

The FDA has approved Niktimvo for the treatment of chronic graft-versus-host disease after failure of at least two ...

AUGUST 15, 2024

Strides Made in the ‘Slow Game’ of Conquering cGVHD

Organ and tissue transplantation is known to save lives, but it brings disadvantages, too.

FEBRUARY 17, 2023

New Pediatric Indication for Ibrutinib Granted to Treat GVHD

The FDA granted a new indication for Imbruvica for children 12 months of age and older with cGVHD after failure of ...

AUGUST 25, 2022

New Approvals for GVHD Expand Treatment Options

For years, therapeutic options for graft-versus-host disease (GVHD) had been limited. Although several recent ...

AUGUST 17, 2022

Jakafi Approved To Treat Chronic GVHD in Adults and Children

The FDA approved ruxolitinib (Jakafi, Incyte) for chronic graft-versus-host disease after failure of one or two ...

OCTOBER 15, 2021

Oral JAK Inhibitor Shows Efficacy for Steroid-Refractory Graft-Versus-Host Disease

The oral JAK inhibitor ruxolitinib is associated with significant clinical improvement in patients with ...

JANUARY 29, 2021

FDA Approves Jakafi to Treat Acute GVHD

The FDA granted a new indication for Jakafi to treat steroid-refractory acute graft-versus-host disease in adults ...

MAY 28, 2019

Low-Dose IL-2, Abatacept Show Benefit in GVHD

Researchers are making progress in efforts to combat the dangerous, often deadly, graft-versus-host disease that ...

JANUARY 18, 2018

FDA Approves Imbruvica to Treat Adults With Chronic GVHD

Imbruvica becomes the first and only therapy specifically approved for adults with cGVHD, a serious and ...

AUGUST 7, 2017

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