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PCSK9 inhibitors

Novel Gene Therapy Slashes LDL in Patients With Hypercholesterolemia

VERVE-101, a novel gene therapy using liquid nanoparticles to edit the PCSK9 gene, reduced LDL cholesterol ...

NOVEMBER 17, 2023

Early Treatment With Repatha Lowered Incidence of CV Death, Other Events

Long-term treatment with evolocumab in adults with atherosclerosis lowered the incidence of major cardiovascular ...

SEPTEMBER 8, 2022

Amgen Lowers List Price for Repatha for Everyone

Effective Dec. 31, 2019, evolocumab will be distributed exclusively at the 60% lower list price of $5,850 per year ...

OCTOBER 24, 2019

Cost of Praluent PCSK9 Inhibitor Lowered for Medicare Patients

The cost of Praluent, regardless of dose, will be $5,850 annually, a 60% reduction from the original price.

FEBRUARY 12, 2019

Some Still Apprehensive About PCSK9 Therapy

Even when prescriptions for costly PCSK9 inhibitors are approved by insurers for the management of low-density ...

AUGUST 30, 2018

PBM Abarca Announces Outcomes-Based Contract for Amgen’s Evolocumab

Innovative PBM Abarca has entered into an outcomes-based contract for the PCSK9 inhibitor evolocumab with Amgen, ...

MARCH 9, 2018

New Indication Granted for Repatha for Wider Group of Patients: Adults with CVD

Repatha's indication had been limited to patients with homozygous familial hypercholesterolemia who require ...

DECEMBER 2, 2017

Most Insurers Denying Claims for PCSK9 Inhibitors

PCSK9 inhibitors, such as Repatha and Praluent have been shown to reduce low-density lipoprotein by 60% and ...

NOVEMBER 29, 2017

PCSK9s Effective, but Give Statins a Chance

Although the exact role of LDL cholesterol–lowering drugs in managing cardiovascular disease is still being ...

JUNE 4, 2017

Elevated Cataract Risk Seen in Some PCSK9-Treated Patients

PCSK9 inhibitors can reduce a high percentage of LDL cholesterol in high-risk patients, but there have been some ...

FEBRUARY 1, 2017

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